99% Veterinary Medicine Florfenicol

99% Veterinary Medicine Florfenicol

Model NO.: Florfenicol
Component: Animal
Pharmacodynamic Influential Factors: Animal Species
Veterinary Reg. No.: N/M
Standard: USP/Bp/Ep
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Product Details

Basic Info

● Model NO.: Florfenicol

● Component: Animal

● Pharmacodynamic Influential Factors: Animal Species

● Veterinary Reg. No.: N/M

● Standard: USP/Bp/Ep

● Apply to: Poultry, Fowl, Pig

● Transport Package: 25kg/Drum

● Origin: Jiangxi

● Varieties: General Disease Prevention Medicine

● Type: Antibiotic, The First Class

● Storage Method: Light Proof

● Shelf Life Time: 2 Years

● Appearance: White Crystall Powder

● Trademark: FMN

● Specification: 99%

● HS Code: 2942000000


Product Description

This product is a derivative of florfenicol, which is designed according to the principle of the prodrug. It has a effect on a variety of Gram-positive bacteria, Gram-negative bacteria and mycoplasma. Its antibacterial mechanism is mainly by binding with the 50S ribosome subunit to inhibit the key enzyme of protein synthesis, the peptidyl transferase, which specifically prevents the binding of the amyl tRNA from the ribosome, and inhibits the elongation of the peptide chain so that the protein can not be synthesized. The MIC50 and MIC90 of the pathogenic bacteria of bovine respiratory disease were (MIC50) and MIC90 respectively: 0.50, 1, 0.50, 0.50 of the haemolysin, and the MIC of Actinobacillus pleuropneumoniae was 0.2-1.56 g/ml. 


The MIC of Shigella dysenteriae, Salmonella typhimurium, Escherichia coli and ampicillin resistant Haemophilus influenzae, which were resistant to chloramphenicol and methicillomycin, were 0.5 g/ml. This product not only increases its water solubility, but also reduces the loss of the body after oral and injection. Through the metabolic decomposition of biological enzymes in the body, the esters and florfenicol are released and the esters overcome the resistance of bacteria. The target orientation of florfenicol plays a very important role in the organism. It has small dosage, fast effect, long half-life, high blood concentration, and can maintain the blood drug concentration for a long time. Mainly through the kidney excretion. It is applied to soluble powder, oral liquid, injection and other dosage forms. Florfenicol succinic acid sodium


items

specifications

results

appearance

white crystalline powder

white crystalline powder

identification

the rt is same with standard sample in hplc system

conforms

ph

4.5 ~ 7.0

5.10

melting point

153℃ ~ 158℃

154.5℃~155.5℃

optical rotation

-15° ~ -20°

-17.8°

loss on drying

≤ 0.50%

0.10%

heavy metal

≤ 0.002%

conforms

total impurities

≤ 2.0%

0.70%

max impurity

≤ 0.50%

0.24%

assay (anhydrous)

98% min

99.3%

conclusion

this conforms to enterprise standard

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