99% Doxycycline Powder

99% Doxycycline Powder

Model NO.: 564-25-0
Other Names: Doxycycline HCl
Mf: C22h24n2o8
Einecs No.: 209-271-1
Grade Standard: Medicine Grade

Product Details

Basic Info

Model NO.: 564-25-0
Other Names: Doxycycline HCl
Mf: C22h24n2o8
Einecs No.: 209-271-1
Grade Standard: Medicine Grade
Usage: Animal Pharmaceuticals
Testing Method: HPLC
Appearance: Light Yellow Powder
Trademark: wongpharm
Transport Package: 25kg/Drum
Specification: 90%
Origin: Jiangsu China (Mainland)


Product Description
It is mainly used to treat respiratory tract, urinary tract and biliary tract infection caused by sensitive bacteria. The antibacterial spectrum is basically the same as tetracycline and oxytetracycline, and the antibacterial activity in vivo and in vitro is stronger than that of tetracycline. Microorganisms have close cross resistance to tetracycline and oxytetracycline. The oral absorption is good. It is mainly used for the upper respiratory tract infection, tonsillitis, biliary tract infection, lymphadenitis, cellulitis, senile chronic bronchitis and so on, and also for the treatment of typhus, Qiang insect disease, mycoplasma pneumonia and so on. It can also be used to treat cholera and to prevent falciparum malaria and leptospirosis infection. 


In the long-term treatment practice, it is found that doxycycline is a good antiseptic. It is a long-acting and broad-spectrum semi synthetic tetracycline antibiotic made from oxytetracycline, and the reason for the better effect of doxycycline in the treatment of chronic bronchitis is due to:

(1) the antibacterial spectrum is wide, and the antibacterial effect is strong. In addition to having positive effects on Gram-positive bacteria and negative bacteria, Rickettsia and pneumonia can also be suppressed.
Mycoplasma, Mycoplasma trachoma, amoeba protozoa, etc. In particular, the common respiratory tract bacteria in patients with chronic bronchitis are more sensitive to doxycycline.

(2) to maintain a long time, after oral absorption faster, 3 hours after the maximum effect, mainly by the slow excretion of the kidney, adult oral 200 mg once, 24 hours in 32%, 48 hours of excretion of 41%, effective blood drug concentration than tetracycline, oxytetracycline long, more suitable for treatment of chronic inflammation. Oral dosage first days 0.2 grams, after taking 1 times a day, 0.1 grams (100 mg) each time.

(3) doxycycline has a certain antitussive, expectorant and antiasthmatic effect, which have been confirmed by animal experiments, and further explain the reasons for the better efficacy of doxycycline in the treatment of chronic bronchitis.


ITEMS

SPECIFICATION

RESULTS

BP2010 /EP6

Appearance

crystalline powder

Conforms

Melting point

About 205°C

206.4°C~206.7°C

Identification

Meet the requirements

Conforms

Appearance of solution

Clear, not more intense than Y7

Conforms

pH

2.4~3.0

2.60

Loss on drying

≤0.5%

0.04%

Sulphated ash

≤0.1%

0.01%

Heavy metals

≤20 ppm

<20 ppm

Related substances

≤0.25%

Conforms

Assay

99.0%~101.0%

99.8%

USP32

Identification

Meet the requirements

Conforms

Loss on drying

≤0.5%

0.04%

Residue on ignition

≤0.1%

0.01%

Heavy metals

≤0.003%

<0.003%

Residue solvent - Ethanol

≤0.5%

<0.04%

Chloride

16.9%~17.6%

17.1%

Assay

98.0%~102.0%

100.0%

Conclusion: The product complies with BP2010/USP32/EP6 standard

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