New Nonsteroidal Eye Drugs Nepafenac

New Nonsteroidal Eye Drugs Nepafenac

Product name :New nonsteroidal eye drugs Nepafenac CAS No: 78281-72-8 Molecular Formula: C15H14N2O2 Appearance: Light yellow crystalline powder Application: New nonsteroidal antipyretic, analgesic and anti-inflammatory drugs for eyes Package: according to the clients requirement Port: Shanghai Production Capacity: 500kg/month Purity: 99% Storage: Keep in cool, dry and sealed Transportation: by sea or by air MOQ:1kg
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Product Details

Product name :New nonsteroidal eye drugs Nepafenac

CAS No: 78281-72-8

Molecular Formula: C15H14N2O2

Appearance: Light yellow crystalline powder

Application: New nonsteroidal antipyretic, analgesic and anti-inflammatory drugs for eyes

Package: according to the clients requirement

Port: Shanghai

Production Capacity: 500kg/month

Purity: 99%

Storage: Keep in cool, dry and sealed

Transportation: by sea or by air



Product Description


After administration by the eye, neparfentine can rapidly pass through the cornea and be converted into aminophen acid (a kind of NSAID) by hydrolase in the eye tissue. In addition, aminophen acid exerts its anti-inflammatory and analgesic effects by inhibiting prostaglandin H synthase (cyclooxygenase) and blocking the synthesis of prostaglandin. As known to all, prostaglandins are one of the mediators of intraocular inflammation, which can lead to the collapse of the blood-aqueous barrier, vasodilatation, increased vascular permeability and leukocyte chemotaxis, etc. In addition, prostaglandins can also contract the iris sphincter through the non-cholinergic mechanism, which can trigger the pupil contraction during and after eye surgery. NSAIDs can inhibit the synthesis of prostaglandin in the iris, ciliary body and conjunctiva after ocular administration, so as to prevent the occurrence of eye inflammation and reduce related pain

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