Cinnamic Aldehyde Will Appear In Various Parts Of The Body After Entering The Body

- Jun 12, 2018-

Cinnamic aldehyde will appear in various parts of the body after entering the body, and almost all of the metabolites produced will be excreted. Intravenous injection of Cinnamic aldehyde in rats showed that the Cinnamic aldehyde in the blood rapidly decreased with time, most Cinnamic aldehyde will be excreted in the form of hippuric acid, and a small part will be in the form of glucoside-cinnamic acid or free cinnamic acid. Excreted. Cinnamic aldehyde will appear in different parts of the body after entering the body, in which the blood and muscle content is high, indicating that Cinnamic aldehyde or its metabolites will be distributed in different parts of the body after absorption into the body. Test results showed that approximately 94% of Cinnamic aldehyde was excreted in urine and feces after 72 hours.

The main metabolite of Cinnamic aldehyde is cinnamic acid, and Cinnamic aldehyde has strong antioxidation and antibacterial ability. However, there are few reports on the antioxidation or antibacterial ability of cinnamic acid. Cinnamic aldehyde has the function of inhibiting the proliferation of gram-negative bacilli, and at the same time it can enhance the antioxidant capacity of animals and reduce or alleviate the inflammatory response. The antibacterial activity and antioxidative activity of Cinnamic aldehyde are related to aldehyde groups. The aldehyde group of Cinnamic aldehyde is easily adsorbed by the hydrophilic group on the surface of the bacteria and enters the cell wall, destroying the polysaccharide structure of the cell wall of bacteria and fungi, thereby exerting an antibacterial effect. The mechanism of action of cinnamic acid remains to be studied. It has been found in studies of isoproterenol (ISO)-induced cardiomyopathy that both Cinnamic aldehyde and cinnamic acid have the ability to improve the serum antioxidative enzyme activity and inflammatory factor changes induced by ISO, and The effect is similar. Another study found that when Cinnamic aldehyde was converted to cinnamic acid, there was no clearance effect on O2. It is suggested that cinnamic acid may enhance the antioxidant capacity of the body through other ways in vivo.

Cinnamic aldehyde can affect animal body through anti-inflammatory, anti-oxidation and bacteriostasis. However, because Cinnamic aldehyde has a strong reducibility, it is inevitably oxidized by the oxidizing substances in the process of eating, digestion and absorption to reduce their effectiveness. In order to better exert the anti-oxidation and bacteriostatic properties of Cinnamic aldehyde, its active ingredients must be protected by coating and other processing techniques, so as to ensure that the target can achieve its leading role.