Indacaterol Maleate

Indacaterol Maleate

Product name :Indacaterol Maleate CAS No: 753498-25-8 Molecular Formula: C24H28N2O3 Appearance: White or whitish powder Application: bronchodilatation Package: according to the clients requirement Port: Shanghai Production Capacity: 500kg/month Purity: 98% Storage: Keep in cool, dry and sealed Transportation: by sea or by air MOQ:1kg
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Product Details

Product name :Indacaterol Maleate

CAS No: 753498-25-8

Molecular Formula: C24H28N2O3

Appearance: White or whitish powder

Application: bronchodilatation

Package: according to the clients requirement

Port: Shanghai

Production Capacity: 500kg/month

Purity: 98%

Storage: Keep in cool, dry and sealed

Transportation: by sea or by air

MOQ:1kg

 

 

Product Description

 

Indanterol is a long - acting 2- adrenergic receptor agonist.

Indanterol ACTS as a local bronchodilator in the lung after inhalation. Although beta2-receptors are the major adrenergic receptors in bronchial smooth muscle and beta1-receptors are the major receptors in the heart, there are also beta2-adrenergic receptors in the human heart, accounting for 10% to 50% of the total adrenergic receptors. Although the exact function of these receptors is unknown, their presence suggests the possibility that even highly selective 2-adrenergic agonists may have an effect on the heart.

 

The pharmacological action of 2-adrenergic agonist drugs, including indanadrol, is at least partially due to the activation of intracellular adenosine cyclase, which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic 3', 5' -adenosine monophosphate (cyclic adenosine monophosphate). Elevated levels of cyclic adenosine phosphate (cAMP) cause relaxation of bronchial smooth muscle. In vitro studies showed that the long acting beta2-adrenergic agonist indanterol was 24 times more agonist than beta1-receptor and 20 times more agonist than beta3-receptor. The clinical significance of these findings is unclear.


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