Product name :Arformoterol tartrate
CAS No: 200815-49-2
Molecular Formula: C19H24N2O4.C4H6O6
Appearance: white powder
Application: It is suitable for chronic obstructive pulmonary disease
Package: according to the clients requirement
Production Capacity: 500kg/month
Storage: Keep in cool, dry and sealed
Transportation: by sea or by air
This product is suitable for long-term maintenance of bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
This product is a kind of selective long-acting -2 receptor agonist, which can activate adenylate cyclase in vivo. This enzyme can convert adenosine triphosphate (ATP) into 3' -5 '-cyclic adenosine (cAMP). The increase of intracellular cAMP can relax bronchial smooth muscle and reduce the release of allergenic mediators from cells, especially mast cells. In vitro experiments showed that this product can inhibit the release of histamine, leukotriene and other mediators in human lung mast cells. In addition, it inhibits histamine-mediated leakage of plasma albumin from anesthetized guinea pigs, and inhibits allergy-induced influx of eosinophilic cells from airway hyperreactive model dogs. The relevance of these in vitro and animal results to human trials is unclear.