Product name :China supplies high quality bulk drug Nicorandil
CAS No: 65141-46-0
Molecular Formula: C8H9N3O4
Appearance: White crystalline powder
Package: according to the clients requirement
Production Capacity: 1000kg
Storage: Store in a cool, dry place
Transportation: by sea or by air
Coronary artery disease (CHD) can effectively dilate normal coronary arteries and narrow coronary arteries to increase coronary blood flow. It can obviously improve the prognosis of patients with coronary heart disease and reduce all-cause death.
Because of its pharmacological properties, such as dilating coronary arteries, increasing coronary blood flow without increasing myocardial oxygen consumption, and reducing cardiac load, nicodil is effective in the treatment of all types of angina pectoris. Clinical trials have proved that one oral administration of nicodil can prolong the time from exercise to angina attack and the decrease of ST segment of electrocardiogram to 1mm in patients with angina, and the dosage is positively correlated with the extended time, and the efficacy can be maintained for about 6h. It can control angina pectoris attack, the effective rate of about 90%. With the prolonging of treatment course, the frequency of attack decreased obviously.
Protective cardiomyocyte nichodil can reduce calcium influx, relax the matrix, and increase volume, thereby promoting cardiac respiration and energy generation, simulating ischemic preconditioning, and protecting cardiomyocytes.
Other diseases caused by microvascular circulation (e.g., pulmonary hypertension)