China Supplies High Quality Bulk Drug Nicorandil

China Supplies High Quality Bulk Drug Nicorandil

Product name :China supplies high quality bulk drug Nicorandil CAS No: 65141-46-0 Molecular Formula: C8H9N3O4 Appearance: White crystalline powder Application: antiangina Package: according to the clients requirement Port: Shanghai Production Capacity: 1000kg Purity: 98% Storage: Store in a cool, dry place Transportation: by sea or by air MOQ:1kg

Product Details

Product name :China supplies high quality bulk drug Nicorandil

CAS No: 65141-46-0

Molecular Formula: C8H9N3O4

Appearance: White crystalline powder

Application: antiangina

Package: according to the clients requirement

Port: Shanghai

Production Capacity: 1000kg

Purity: 98%

Storage: Store in a cool, dry place

Transportation: by sea or by air

MOQ:1kg

 

 

Product Description

 

Clinical application

 

Coronary artery disease (CHD) can effectively dilate normal coronary arteries and narrow coronary arteries to increase coronary blood flow. It can obviously improve the prognosis of patients with coronary heart disease and reduce all-cause death.

 

Because of its pharmacological properties, such as dilating coronary arteries, increasing coronary blood flow without increasing myocardial oxygen consumption, and reducing cardiac load, nicodil is effective in the treatment of all types of angina pectoris. Clinical trials have proved that one oral administration of nicodil can prolong the time from exercise to angina attack and the decrease of ST segment of electrocardiogram to 1mm in patients with angina, and the dosage is positively correlated with the extended time, and the efficacy can be maintained for about 6h. It can control angina pectoris attack, the effective rate of about 90%. With the prolonging of treatment course, the frequency of attack decreased obviously.

 

Protective cardiomyocyte nichodil can reduce calcium influx, relax the matrix, and increase volume, thereby promoting cardiac respiration and energy generation, simulating ischemic preconditioning, and protecting cardiomyocytes.

 

 

 

Other diseases caused by microvascular circulation (e.g., pulmonary hypertension)


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