CAS No.: 106308-44-5
Other Names: Rufinamide
EINECS No.: 200-659-6
Place of Origin: wuhan, China (Mainland)
Type: Antibiotic and Antimicrobial Agents
Grade Standard: Medicine Grade
Brand Name: Dahua
Model Number: USP 39
Test Standard: EP 9.0/USP39/BP2015
Content: 99.0% to 101.0%
Test method: HPLC-ESI-MS
Water: 0.5% Max.
Sulfated ash: 0.1% Max.
Heavy metals: 10ppm Max
Total Impurity: 0.5% Max.
Total plate count: ≤1000cfu/g
Yeast and Moulds: ≤100cfu/g
100 Ton/Tons per Year
Packaging & Delivery
Any main port of China
Lead Time: 10 Days
A.H-NMR:Comply with the structure
B.LC-MS:Comply with the structure
C.The IR spectrum of sample should be identical with that of reference standard;
meets the requirements.
Loss on drying
≤0.5%, determined on 1.0 g.
Unspecified impurities: for each impurity
99.0%~101.0% (anhydrous substance).
Total plate count
Yeast and Moulds
Preserve in well-closed, light-resistant and airtight containers.
a) Free sample can be supplied.
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c) Accpet SGS,BV any other third-party inspection before loading
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A) High quality can be guaranteed. Dideu Industries since 1975 are reputed chemical manufacturer and are Certified by ISO,GMP,FDA and have CEP/COS certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P,D/A payment term. If there is any quality problem after goods arrive. Dideu Industries will do fully payment refund.
B) Best price can be guaranteed. As Dideu Industries are integrated pharmaceuticals and chemicals producer the production cost can be controlled and price will be definitely more competitive than China trading companies.
C) Professional enginners from Dideu Industries will give professional usage guide and services after sales.
D) Dideu Industries work 7×24 hours and your request will be processed by our professional staff in different shift period.
Rufinamide is an anticonvulsant medication. It is used in combination with other medication and therapy to treat Lennox–Gastaut syndrome and various other seizure disorders. Rufinamide, a triazole derivative, was developed in 2004 by Novartis Pharma, AG, and is manufactured by Eisai.
Rufinamide was approved by the US Food and Drug Administration on November 14, 2008 as adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in children 4 years and older and adults. Its official FDA-approved labeling does not mention use in the treatment of partial seizures inasmuch as clinical trials submitted to the FDA were marginal. However, several recent clinical trials suggest that the drug has efficacy for partial seizures It is marketed under the brand name Banzel. It is also marketed in the European Union under the brand name Inovelon.
The mechanism of action of rufinamide is unknown. There is some evidence that rufinamide can modulate the gating of voltage-gated sodium channels, a common target for antiepileptic drugs. A recent study indicates subtle effects on the voltage-dependence of gating and the time course of inactivation in some sodium channel isoforms that could reduce neuronal excitability.However, this action cannot explain the unique spectrum of activity of rufinamide.