Pramoxine HCl

Pramoxine HCl

Quick Details Product name : Pramoxine HCl CAS 637-58-1 Pramoxine hydrochloride powder CAS No.: 637-58-1 Other Names: Pramoxine hydrochloride MF: C17H28ClNO3 EINECS No.: 211-293-1 Place of Origin: hubei, China (Mainland) Type: Anesthetic Agents Grade Standard: Medicine Grade Brand Name: Dahua...
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Product Details

Quick Details

Product name : Pramoxine HCl CAS 637-58-1 Pramoxine hydrochloride powder
CAS No.: 637-58-1
Other Names: Pramoxine hydrochloride
MF: C17H28ClNO3
EINECS No.: 211-293-1
Place of Origin: hubei, China (Mainland)
Type: Anesthetic Agents
Grade Standard: Medicine Grade
Brand Name: Dahua chem
Model Number: API
Purity: >99%
Pramocaine HCl Color: Crystals
Pramocaine HCl Melting Point: 181-183
Pramocaine HCl Solubility: >49.5 [ug/mL]
Pramocaine HCl Quality standard: USP
Pramocaine HCl Brand: dahua CHEM
Pramocaine HCl Grade: Pharma Grade
Pramocaine HCl Type: API

SupplyAbility
5000 Kilogram/Kilograms per Month Pramocaine HCl, CAS 637-58-1, Medicine Grade

Packaging & Delivery
Packaging Details
For small quantity: Bag
Commercial quantity: fiber drum
Or as per customers required
Port: Any port in China
Lead Time: Shipped in 3 days after payment
 

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Identification

Name

Pramoxine HCl,Pramoxine hydrochloride,CAS 637-58-1

Structure

图片9_副本.jpg

Other name

Pramoxine hydrochloride
637-58-1
Pramoxine HCl
Pramocaine hydrochloride
Tronothane hydrochloride
Pramocaine (hydrochloride)

Key words

Pharmaceutical ingredients, API, anesthetic agent; used as an antipruritic

CAS NO.

637-58-1

Molecular Formula

C17H28ClNO3

Molecular Weight

329.865 g/mol


Chemical and Physical Properties

Color

Crystals

Melting Point

181-183 deg C

Solubility

>49.5 [ug/mL]

Quality standard

USP


Application

Drug Indication

used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches.

Formulations/Preparations

pramoxine hydrochloride cream or ointment


Handling and storage

Safety and Hazards

The shanghai Research Institute of Chemical industry testing center identification conclusion :1 None hazard identification, 2 The substance is not subject to IATA DGR, 3 Non packing requirements.

Handling and storage

Keep container tightly closed in a dry and well-ventilated place. Light sensitive.

Sample package

Aluminium foil bag

Commercial package

Fiber drum

UN Code

Not classfied

HS Code

29349990.9

Shipping group

Shipment at ambient temperature for no controlled and  no dangerous goods

Sales restriction

NO

Origin

China


Technical Support

Pramocaine HCl STD Data sheet

Yes

Pramocaine HCl MSDS

Yes

Pramocaine HCl COA

Yes

Pramocaine HCl Transport certificate

Yes


Supply ability

Monthly capacity

5000kg

GMP

None


Related APIs

Related APIS

Cyproheptadine
Diphenhydramine hcl


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Superiority:
pramocaine hcl(inn and ban, also known as pramoxine or pramoxine hci) is a topical anesthetic discovered at abbott laboratories in 1953,and used as an antipruritic. during research and development, pramocaine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.] pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans. like other local anesthetics, pramocaine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.
topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. the popular itch creams gold bond and some forms of calamine lotion use pramocaine hydrochloride to numb sensitive skin, as does the pain relief variant of neosporin and some formulations of sarna. the hydrochloride salt form of pramocaine is water-soluble.
pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.

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