Product name :Macrolide antibiotics Tacrolimus
CAS No: 104987-11-3
Molecular Formula: C44H69NO12
Appearance: white powder
Application:Immunosuppressive drugs are preferred for liver and kidney transplantation
Package: according to the clients requirement
Port: Shanghai
Production Capacity: 500kg/month
Purity: 99%
Storage: Keep in cool, dry and sealed
Transportation: by sea or by air
MOQ:1kg
Product Description
Tacrolimus is a macrolide isolated from Streptomyces genus, which has a strong immunosuppressive effect. It can specifically bind and inhibit the activity of calmodulin phosphatase, inhibit the transcription of il-2 signal, and thereby inhibit the activation of T cells, the production of TNF-, il-1 and il-6, and the proliferation of T cell-dependent B cells. Compared with cyclosporine, another calmodulin phosphatase inhibitor, tacrolimus has a stronger inhibitory effect on T cell activation with fewer adverse reactions.
Macrolide antibiotics. Immunosuppressant. The mechanism of action is the same as that of cyclosporine, mainly inhibiting the synthesis of interleukin-2. Rejection of organ transplantation.
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