Macrolide Antibiotics Tacrolimus

Macrolide Antibiotics Tacrolimus

Product name :Macrolide antibiotics Tacrolimus CAS No: 104987-11-3 Molecular Formula: C44H69NO12 Appearance: white powder Application:Immunosuppressive drugs are preferred for liver and kidney transplantation Package: according to the clients requirement Port: Shanghai Production Capacity: 500kg/month Purity: 99% Storage: Keep in cool, dry and sealed Transportation: by sea or by air MOQ:1kg

Product Details

 

Product name :Macrolide antibiotics Tacrolimus

CAS No: 104987-11-3

Molecular Formula: C44H69NO12

Appearance: white powder

Application:Immunosuppressive drugs are preferred for liver and kidney transplantation

 Package: according to the clients requirement

Port: Shanghai

Production Capacity: 500kg/month

Purity: 99%

Storage: Keep in cool, dry and sealed

Transportation: by sea or by air

MOQ:1kg

 

 

Product Description

 

Tacrolimus is a macrolide isolated from Streptomyces genus, which has a strong immunosuppressive effect. It can specifically bind and inhibit the activity of calmodulin phosphatase, inhibit the transcription of il-2 signal, and thereby inhibit the activation of T cells, the production of TNF-, il-1 and il-6, and the proliferation of T cell-dependent B cells. Compared with cyclosporine, another calmodulin phosphatase inhibitor, tacrolimus has a stronger inhibitory effect on T cell activation with fewer adverse reactions.

 

Macrolide antibiotics. Immunosuppressant. The mechanism of action is the same as that of cyclosporine, mainly inhibiting the synthesis of interleukin-2. Rejection of organ transplantation.

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